Announcement PDF Appendix 3Z Final Director’s Interest Notice + See chapter 19 for defined terms. 11/3/2002 Appendix 3Z Page 1 Rule 3.19A.3 Appendix 3Z Final Director’s Interest Notice Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public. Introduced 30/9/2001. Name of entity Avecho Biotechnology Limited ABN 32 056 482 403 We (the entity) give ASX the following information under listing rule 3.19A.3 and as agent for the director for the purposes of section 205G of the Corporations Act. Name of director Matthew Patrick McNamara Date of last notice 13 May 2026 Date that director ceased to be director 25 May 2026 Part 1 – Director’s relevant interests in securities of which the director is the registered holder In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part. Number & class of securities Direct N/A Appendix 3Z Final Director’s Interest Notice + See chapter 19 for defined terms. Appendix 3Z Page 2 11/3/2002 Part 2 – Director’s relevant interests in securities of which the director is not the registered holder Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part. In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust Name of holder & nature of interest Note: Provide details of the circumstances giving rise to the relevant interest PELEHJ145 PTY LTD <M & L MCNAMARA SFA/C> Pelehj145 Pty Ltd <M&L McNamara Super Fund> Number & class of securities 1,666,666 Fully Paid Ordinary Shares (AVE) 1,584,648 Unquoted Options exercisable at $0.0066 each (AVEAS).* * Of the 3,169,298 Unquoted Options previously held, 1,584,650 lapsed on 25 May 2026 and 1,584,648 are retained. Part 3 – Director’s interests in contracts Detail of contract N/A Nature of interest N/A Name of registered holder (if issued securities) N/A No. and class of securities to which interest relates N/A